人 MPP5 (NM_001256550) cDNA克隆

Accession: NM_001256550
基因名称: MPP5
基因别名: PALS1
基因描述: Homo sapiens membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) (MPP5), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1926 (查看编码区序列)
翻译后氨基酸长度: 641 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate in-frame splice site, lacks a portion of the 5' coding region and initiates translation at a downstream start codon compared to variant 1. The resulting protein (isoform 2) has a shorter N-terminus compared to isoform 1.
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G125007 人 MPP5 (NM_001256550) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the p55-like subfamily of the membrane-associated guanylate kinase (MAGUK) gene superfamily. The encoded protein participates in the polarization of differentiating cells, has been shown to regulate myelinating Schwann cells (PMID: 20237282), and is one of the components of the Crumbs complex in the retina. Mice which express lower levels of the orthologous protein have retinal degeneration and impaired vision (PMID: 22114289). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]