人 ESRRA (NM_001282450) cDNA克隆

Accession: NM_001282450
基因名称: ESRRA
基因别名: ERR1; ERRa; ESRL1; NR3B1; ERRalpha
基因描述: Homo sapiens estrogen-related receptor alpha (ESRRA), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1272 (查看编码区序列)
翻译后氨基酸长度: 423 (查看氨基酸序列)
Transcript Variant: This variant (2) has an alternate 5' UTR exon, compared to variant 1. Both variants 1 and 2 encode the same protein.
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G125098 人 ESRRA (NM_001282450) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]