COMMD6 belongs to a family of NF-kappa-B (see RELA; MIM 164014)-inhibiting proteins characterized by the presence of a COMM domain (see COMMD1; MIM 607238) (de Bie et al., 2006 [PubMed 16573520]).[supplied by OMIM, Mar 2009]
| Accession: | NM_001287394 |
|---|---|
| 基因名称: | COMMD6 |
| 基因别名: | Acrg |
| 基因描述: | Homo sapiens COMM domain containing 6 (COMMD6), transcript variant 5, mRNA. |
| 种属: | Human |
| CDS区长度: | 177 (查看编码区序列) |
| 翻译后氨基酸长度: | 58 (查看氨基酸序列) |
| Transcript Variant: | This variant (5) contains a novel 5' terminal exon, lacks 2 exons in the 5' region (which result in translation initiation from an in-frame downstream start codon) and an in-frame coding exon in the 3' region compared to variant 1. The resulting isoform (c) has a shorter N-terminus and lacks a 13 aa protein segment compared to isoform 1. Variants 3-5 encode the same isoform. |
| 人 COMMD6 (NM_203497) cDNA克隆 | transcript variant 1 |
| 人 COMMD6 (NM_203495) cDNA克隆 | transcript variant 2 |
| 人 COMMD6 (NM_001287392) cDNA克隆 | transcript variant 3 |
| 人 COMMD6 (NM_001287393) cDNA克隆 | transcript variant 4 |
| 人 COMMD6 (NM_001287394) cDNA克隆 | transcript variant 5 |
COMMD6 belongs to a family of NF-kappa-B (see RELA; MIM 164014)-inhibiting proteins characterized by the presence of a COMM domain (see COMMD1; MIM 607238) (de Bie et al., 2006 [PubMed 16573520]).[supplied by OMIM, Mar 2009]