人 POU5F1 (NM_002701) cDNA克隆

基本信息

Accession: NM_002701
基因名称: POU5F1
基因别名: OCT3; OCT4; OTF3; OTF4; OTF-3; Oct-3; Oct-4
基因描述: Homo sapiens POU class 5 homeobox 1 (POU5F1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1083 (查看编码区序列)
翻译后氨基酸长度: 360 (查看氨基酸序列)
Transcript Variant: This variant (1, also known as OCT4A) represents the shortest transcript and encodes the longest isoform (1).

订购信息

产品编号 产品名称 载体 规格 价格
G125686 人 POU5F1 (NM_002701) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 POU5F1 (NM_002701) cDNA克隆 transcript variant 1
人 POU5F1 (NM_203289) cDNA克隆 transcript variant 2
人 POU5F1 (NM_001173531) cDNA克隆 transcript variant 3
人 POU5F1 (NM_001285986) cDNA克隆 transcript variant 4
人 POU5F1 (NM_001285987) cDNA克隆 transcript variant 5

基因简介

This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013]

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