人 SMARCB1 (NM_003073) cDNA克隆

Accession: NM_003073
基因名称: SMARCB1
基因别名: RDT; INI1; SNF5; Snr1; BAF47; MRD15; RTPS1; Sfh1p; hSNFS; SNF5L1
基因描述: Homo sapiens SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 (SMARCB1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1158 (查看编码区序列)
翻译后氨基酸长度: 385 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
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G125712 人 SMARCB1 (NM_003073) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]