SPRED2 is a member of the Sprouty (see SPRY1; MIM 602465)/SPRED family of proteins that regulate growth factor-induced activation of the MAP kinase cascade (see MAPK1; MIM 176948) (Nonami et al., 2004 [PubMed 15465815]).[supplied by OMIM, Mar 2008]
| Accession: | NM_001128210 |
|---|---|
| 基因名称: | SPRED2 |
| 基因别名: | Spred-2 |
| 基因描述: | Homo sapiens sprouty-related, EVH1 domain containing 2 (SPRED2), transcript variant 2, mRNA. |
| 种属: | Human |
| CDS区长度: | 1248 (查看编码区序列) |
| 翻译后氨基酸长度: | 415 (查看氨基酸序列) |
| Transcript Variant: | This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) has a shorter and distinct N-terminus compared to isoform a. |
| 人 SPRED2 (NM_181784) cDNA克隆 | transcript variant 1 |
| 人 SPRED2 (NM_001128210) cDNA克隆 | transcript variant 2 |
SPRED2 is a member of the Sprouty (see SPRY1; MIM 602465)/SPRED family of proteins that regulate growth factor-induced activation of the MAP kinase cascade (see MAPK1; MIM 176948) (Nonami et al., 2004 [PubMed 15465815]).[supplied by OMIM, Mar 2008]