人 MICA (NM_001177519) cDNA克隆

基本信息

Accession: NM_001177519
基因名称: MICA
基因别名: MIC-A; PERB11.1
基因描述: Homo sapiens MHC class I polypeptide-related sequence A (MICA), transcript variant 1 (allele MICA*00801), mRNA.
种属: Human
CDS区长度: 999 (查看编码区序列)
翻译后氨基酸长度: 332 (查看氨基酸序列)
Transcript Variant: This RefSeq represents the MICA*00801 allelic form of variant 1. It contains a 4 nt insertion (rs9279200) that results in a frameshift and truncation of the CDS, compared to variant 1 (allele MICA*001). The resulting isoform (2) has a shorter and distinct C-terminus, compared to isoform 1. The MICA*00801 allele is found in the GRCh37 primary assembly.

订购信息

产品编号 产品名称 载体 规格 价格
G126320 人 MICA (NM_001177519) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 MICA (NM_000247) cDNA克隆 transcript variant 1 (allele MICA*001)
人 MICA (NM_001177519) cDNA克隆 transcript variant 1 (allele MICA*00801)

基因简介

MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]

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