人 TOPORS (NM_005802) cDNA克隆

Accession: NM_005802
基因名称: TOPORS
基因别名: LUN; RP31; P53BP3; TP53BPL
基因描述: Homo sapiens topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase (TOPORS), transcript variant 1, mRNA.
种属: Human
CDS区长度: 3138 (查看编码区序列)
翻译后氨基酸长度: 1045 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
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G126523 人 TOPORS (NM_005802) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a nuclear protein which is serine and arginine rich, and contains a RING-type zinc finger domain. It is highly expressed in the testis, and functions as an ubiquitin-protein E3 ligase. Mutations in this gene are associated with retinitis pigmentosa type 31. Alternatively spliced transcript variants, encoding different isoforms, have been observed for this locus. [provided by RefSeq, Sep 2010]