人 CDKN1C (NM_000076) cDNA克隆

基本信息

Accession: NM_000076
基因名称: CDKN1C
基因别名: BWS; WBS; p57; BWCR; KIP2; p57Kip2
基因描述: Homo sapiens cyclin-dependent kinase inhibitor 1C (p57, Kip2) (CDKN1C), transcript variant 1, mRNA.
种属: Human
CDS区长度: 951 (查看编码区序列)
翻译后氨基酸长度: 316 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a).

订购信息

产品编号 产品名称 载体 规格 价格
G126608 人 CDKN1C (NM_000076) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CDKN1C (NM_000076) cDNA克隆 transcript variant 1
人 CDKN1C (NM_001122630) cDNA克隆 transcript variant 2
人 CDKN1C (NM_001122631) cDNA克隆 transcript variant 3

基因简介

This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

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