人 CITED2 (NM_001168389) cDNA克隆

Accession: NM_001168389
基因名称: CITED2
基因别名: ASD8; MRG1; VSD2; MRG-1; P35SRJ
基因描述: Homo sapiens Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 (CITED2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 828 (查看编码区序列)
翻译后氨基酸长度: 275 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus, compared to isoform 1.
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G126699 人 CITED2 (NM_001168389) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of hypoxia-inducible factor 1-alpha to p300-CH1. Mutations in this gene are a cause of cardiac septal defects. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]