人 DMRT2 (NM_181872) cDNA克隆

Accession: NM_181872
基因名称: DMRT2
基因描述: Homo sapiens doublesex and mab-3 related transcription factor 2 (DMRT2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1686 (查看编码区序列)
翻译后氨基酸长度: 561 (查看氨基酸序列)
Transcript Variant: This variant (3) uses an alternate acceptor splice site at the 3' terminal exon compared to variant 1, resulting in a longer isoform (2) with a distinct C-terminus compared to isoform 1.
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G127062 人 DMRT2 (NM_181872) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. [provided by RefSeq, Apr 2010]