人 CFHR4 (NM_001201551) cDNA克隆

基本信息

Accession: NM_001201551
基因名称: CFHR4
基因别名: FHR4; CFHL4; FHR-4
基因描述: Homo sapiens complement factor H-related 4 (CFHR4), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1734 (查看编码区序列)
翻译后氨基酸长度: 577 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate acceptor splice site in the 5' coding region compared to variant 1, resulting in an isoform (2) shorter by 1 aa compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G127413 人 CFHR4 (NM_001201551) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CFHR4 (NM_001201550) cDNA克隆 transcript variant 1
人 CFHR4 (NM_001201551) cDNA克隆 transcript variant 2
人 CFHR4 (NM_006684) cDNA克隆 transcript variant 3

基因简介

This gene is a member of the complement factor H (CFH) gene family, and encodes one of the 5 CFH-related (CFHR) proteins. These 5 genes are closely linked to the CFH gene on chromosome 1q31-q32. The CFHRs are secreted plasma proteins synthesized primarily by the hepatocytes, and composed of highly-related short consensus repeats (SCRs). This protein enhances the cofactor activity of CFH, and is involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. Alternatively spliced transcript variants encoding different isoforms (varying in the number of SCRs) have been described for this gene. [provided by RefSeq, Jan 2011]

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