人 CHD3 (NM_001005271) cDNA克隆

基本信息

Accession: NM_001005271
基因名称: CHD3
基因别名: ZFH; Mi-2a; Mi2-ALPHA
基因描述: Homo sapiens chromodomain helicase DNA binding protein 3 (CHD3), transcript variant 3, mRNA.
种属: Human
CDS区长度: 6180 (查看编码区序列)
翻译后氨基酸长度: 2059 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR and CDS, compared to variant 1, resulting in a longer protein (isoform 3) that has a distinct N-terminus, compared to isoform 1. The transcript is supported by ESTs and an mRNA but the predicted protein has not yet been confirmed experimentally.

订购信息

产品编号 产品名称 载体 规格 价格
G127713 人 CHD3 (NM_001005271) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CHD3 (NM_001005273) cDNA克隆 transcript variant 1
人 CHD3 (NM_005852) cDNA克隆 transcript variant 2
人 CHD3 (NM_001005271) cDNA克隆 transcript variant 3

基因简介

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

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