小鼠 Acox1 (NM_001271898) cDNA克隆

Accession: NM_001271898
基因名称: Acox1
基因别名: AOX; Acox; Paox; D130055E20Rik
基因描述: Mus musculus acyl-Coenzyme A oxidase 1, palmitoyl (Acox1), transcript variant 2, mRNA.
种属: Mouse
CDS区长度: 1986 (查看编码区序列)
翻译后氨基酸长度: 661 (查看氨基酸序列)
Transcript Variant: This variant (2) has multiple differences in the coding region but maintains the reading frame, compared to variant 1. This variant encodes isoform 2, which is the same length as isoform 1.
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G128061 小鼠 Acox1 (NM_001271898) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the acyl-coenzyme A oxidase family. The encoded protein is localized to peroxisomes and is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-coenzyme A to 2-trans-enoyl-coenzyme A. Disruption of this gene results in microvesicular steatohepatitis, spontaneous peroxisome proliferation, and the eventual development of hepatocellular carcinomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]