人 ARAP1 (NM_015242) cDNA克隆

基本信息

Accession: NM_015242
基因名称: ARAP1
基因别名: CENTD2
基因描述: Homo sapiens ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 (ARAP1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 3618 (查看编码区序列)
翻译后氨基酸长度: 1205 (查看氨基酸序列)
Transcript Variant: This variant (1) differs in the 5' UTR, compared to variant 3. This difference causes translation initiation at a downstream AUG and an isoform (a) with a shorter N-terminus compared to isoform c.

订购信息

产品编号 产品名称 载体 规格 价格
G128576 人 ARAP1 (NM_015242) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ARAP1 (NM_015242) cDNA克隆 transcript variant 1
人 ARAP1 (NM_001040118) cDNA克隆 transcript variant 3
人 ARAP1 (NM_001135190) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

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