人 AGAP2 (NM_014770) cDNA克隆

基本信息

Accession: NM_014770
基因名称: AGAP2
基因别名: PIKE; GGAP2; CENTG1; RP11-571M6.8
基因描述: Homo sapiens ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 (AGAP2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2511 (查看编码区序列)
翻译后氨基酸长度: 836 (查看氨基酸序列)
Transcript Variant: This variant (2) contains an alternate 5' terminal exon compared to variant 1. This results in a shorter isoform (PIKE-A) with a distinct N-terminus compared to isoform PIKE-L. This isoform is reported to be overexpressed in brain tumors and promote cancer cell invasion (PMID:14761976).

订购信息

产品编号 产品名称 载体 规格 价格
G128578 人 AGAP2 (NM_014770) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 AGAP2 (NM_001122772) cDNA克隆 transcript variant 1
人 AGAP2 (NM_014770) cDNA克隆 transcript variant 2

基因简介

The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

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