人 CLCNKA (NM_001042704) cDNA克隆

Accession: NM_001042704
基因名称: CLCNKA
基因别名: CLCK1; ClC-K1; hClC-Ka
基因描述: Homo sapiens chloride channel, voltage-sensitive Ka (CLCNKA), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2061 (查看编码区序列)
翻译后氨基酸长度: 686 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1, resulting in a protein (isoform 2) that is one amino acid shorter than isoform 1.
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G128881 人 CLCNKA (NM_001042704) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]