小鼠 Ctla4 (NM_001281976) cDNA克隆

Accession: NM_001281976
基因名称: Ctla4
基因别名: Cd152; Ly-56; Ctla-4
基因描述: Mus musculus cytotoxic T-lymphocyte-associated protein 4 (Ctla4), transcript variant 2, mRNA.
种属: Mouse
CDS区长度: 525 (查看编码区序列)
翻译后氨基酸长度: 174 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks the penultimate coding exon, which results in a frame-shift and early translation termination compared to variant 1. The resulting shorter isoform (2, also known as sCTLA-4) with a distinct C-terminus, lacks the transmembrane domain and is secreted (PMIDs: 10831323, 23400950).
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G129511 小鼠 Ctla4 (NM_001281976) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene is a member of the immunoglobulin superfamily, and encodes a protein that functions as a negative regulator of T-cell responses. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2013]