人 OSCAR (NM_001282349) cDNA克隆

Accession: NM_001282349
基因名称: OSCAR
基因别名: PIGR3; PIgR-3
基因描述: Homo sapiens osteoclast associated, immunoglobulin-like receptor (OSCAR), transcript variant 6, mRNA.
种属: Human
CDS区长度: 849 (查看编码区序列)
翻译后氨基酸长度: 282 (查看氨基酸序列)
Transcript Variant: This variant (6) lacks an in-frame exon in the central coding region, compared to variant 1. The encoded isoform (6) is shorter, compared to isoform 1.
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G129697 人 OSCAR (NM_001282349) cDNA克隆 pDONR223 2ug质粒 点击询价

Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]