人 CNR1 (NM_033181) cDNA克隆

基本信息

Accession: NM_033181
基因名称: CNR1
基因别名: CB1; CNR; CB-R; CB1A; CB1R; CANN6; CB1K5
基因描述: Homo sapiens cannabinoid receptor 1 (brain) (CNR1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1320 (查看编码区序列)
翻译后氨基酸长度: 439 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an internal segment near the 5' end of the coding region, compared to variant 1. The resulting protein (isoform b) has a shorter and distinct N-terminus compared to isoform a. PubMed ID: 15620723 referred to this variant and its protein as CB1b.

订购信息

产品编号 产品名称 载体 规格 价格
G129791 人 CNR1 (NM_033181) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CNR1 (NM_016083) cDNA克隆 transcript variant 1
人 CNR1 (NM_033181) cDNA克隆 transcript variant 2
人 CNR1 (NM_001160226) cDNA克隆 transcript variant 3
人 CNR1 (NM_001160258) cDNA克隆 transcript variant 4
人 CNR1 (NM_001160259) cDNA克隆 transcript variant 5

基因简介

This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq, May 2009]

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