小鼠 Cryaa (NM_001278570) cDNA克隆

Accession: NM_001278570
基因名称: Cryaa
基因别名: Crya1; lop18; Acry-1; Crya-1; DAcry-1; AI323437
基因描述: Mus musculus crystallin, alpha A (Cryaa), transcript variant 3, mRNA.
种属: Mouse
CDS区长度: 522 (查看编码区序列)
翻译后氨基酸长度: 173 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an alternate in-frame exon in the coding region compared to variant 1. It encodes isoform 3 which is shorter compared to isoform 1.
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G130094 小鼠 Cryaa (NM_001278570) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes subunit a, one of two subunits of alpha-crystallin, which is a high molecular weight, soluble aggregate and is a member of the small heat shock protein (sHSP) family. It acts as a molecular chaperone and is the major protein in the eye lens, maintaining the transparency and refractive index of the lens. In mouse deficiency in this gene is associated with smaller lenses and eyes and with increasing lens opacity with age. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]