人 GAB3 (NM_001282283) cDNA克隆

基本信息

Accession: NM_001282283
基因名称: GAB3
基因描述: Homo sapiens GRB2-associated binding protein 3 (GAB3), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1647 (查看编码区序列)
翻译后氨基酸长度: 548 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (3) is shorter, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G130876 人 GAB3 (NM_001282283) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 GAB3 (NM_001081573) cDNA克隆 transcript variant 1
人 GAB3 (NM_080612) cDNA克隆 transcript variant 2
人 GAB3 (NM_001282283) cDNA克隆 transcript variant 3

基因简介

This gene is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

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