人 DAZL (NM_001190811) cDNA克隆

Accession: NM_001190811
基因名称: DAZL
基因别名: DAZH; DAZL1; DAZLA; SPGYLA
基因描述: Homo sapiens deleted in azoospermia-like (DAZL), transcript variant 1, mRNA.
种属: Human
CDS区长度: 948 (查看编码区序列)
翻译后氨基酸长度: 315 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
产品编号 产品名称 载体 规格 价格
G132702 人 DAZL (NM_001190811) cDNA克隆 pDONR223 2ug质粒 点击询价

The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]