人 IFNLR1 (NM_170743) cDNA克隆

Accession: NM_170743
基因名称: IFNLR1
基因别名: IFNLR; LICR2; IL28RA; CRF2/12; IL-28R1
基因描述: Homo sapiens interferon, lambda receptor 1 (IFNLR1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1563 (查看编码区序列)
翻译后氨基酸长度: 520 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and it encodes the longest protein (isoform 1).
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G132806 人 IFNLR1 (NM_170743) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]