小鼠 Ltk (NM_008523) cDNA克隆

基本信息

Accession: NM_008523
基因名称: Ltk
基因描述: Mus musculus leukocyte tyrosine kinase (Ltk), transcript variant 1, mRNA.
种属: Mouse
CDS区长度: 1731 (查看编码区序列)
翻译后氨基酸长度: 576 (查看氨基酸序列)
Transcript Variant: This variant (1) is lacking several exons from the 5' end, and an internal coding exon compared to transcript variant 4. This results in a shorter isoform (A), which has a different N-terminus, is missing a 61 aa segment compared to isoform D, and that is localized in the endoplasmic reticulum. This variant is specifically expressed in the lymphocytes and initiates translation from a non-AUG (CUG) start codon.

订购信息

产品编号 产品名称 载体 规格 价格
G133326 小鼠 Ltk (NM_008523) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

小鼠 Ltk (NM_008523) cDNA克隆 transcript variant 1
小鼠 Ltk (NM_206941) cDNA克隆 transcript variant 2
小鼠 Ltk (NM_206942) cDNA克隆 transcript variant 3
小鼠 Ltk (NM_203345) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. Four alternatively spliced transcript variants encoding different isoforms have been described for this gene. These transcripts are expressed in a tissue-specific manner in lymphocytes, brain and neuroblastoma cells, and the encoded isoforms exhibit different subcellular localization. The lymphocyte and brain specific variants initiate translation at non-AUG (CUG) start codons. [provided by RefSeq, Jul 2008]

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