人 ACAN (NM_001135) cDNA克隆

Accession: NM_001135
基因名称: ACAN
基因别名: AGC1; SEDK; AGCAN; CSPG1; MSK16; CSPGCP
基因描述: Homo sapiens aggrecan (ACAN), transcript variant 1, mRNA.
种属: Human
CDS区长度: 7296 (查看编码区序列)
翻译后氨基酸长度: 2431 (查看氨基酸序列)
Transcript Variant: This variant (1) lacks two different segments in the C-terminus, compared to variant 2. The resulting protein (isoform 1) is shorter when it is compared to isoform 2 and lacks the EGF-like and CRP-like domains found in isoform 2.
产品编号 产品名称 载体 规格 价格
G134114 人 ACAN (NM_001135) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene. [provided by RefSeq, Jul 2008]