小鼠 Pomc (NM_001278581) cDNA克隆

Accession: NM_001278581
基因名称: Pomc
基因别名: BE; Npp; ACTH; Clip; Pomc1; Pomc-1; Beta-LPH; alphaMSH; beta-MSH; Gamma-LPH; alpha-MSH; gamma-MSH
基因描述: Mus musculus pro-opiomelanocortin-alpha (Pomc), transcript variant 1, mRNA.
种属: Mouse
CDS区长度: 708 (查看编码区序列)
翻译后氨基酸长度: 235 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, 3, 4, and 5 encode the same protein.
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G135079 小鼠 Pomc (NM_001278581) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing. Processing yields several biologically active peptides, which are involved in diverse cellular functions, such as energy homeostasis, steroidogenesis, and increased melanin production in melanocytes. In mouse deficiency of this gene is associated with obesity, defects in adrenal development, and altered pigmentation. A pseudogene of this gene is located on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]