人 EPS15 (NM_001159969) cDNA克隆

基本信息

Accession: NM_001159969
基因名称: EPS15
基因别名: AF1P; AF-1P; MLLT5
基因描述: Homo sapiens epidermal growth factor receptor pathway substrate 15 (EPS15), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1749 (查看编码区序列)
翻译后氨基酸长度: 582 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks multiple exons at the 5' end and has a distinct 5' UTR and start codon, compared to variant 1. These differences result in a protein (isoform B) with a shorter and distinct N-terminus, compared to isoform A. Isoform B localizes to early endosome membranes.

订购信息

产品编号 产品名称 载体 规格 价格
G136408 人 EPS15 (NM_001159969) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 EPS15 (NM_001981) cDNA克隆 transcript variant 1
人 EPS15 (NM_001159969) cDNA克隆 transcript variant 2

基因简介

This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2009]

相关产品