小鼠 Uba1 (NM_001276316) cDNA克隆

Accession: NM_001276316
基因名称: Uba1
基因别名: Sbx; A1S9; Ube-1; Ube1x
基因描述: Mus musculus ubiquitin-like modifier activating enzyme 1 (Uba1), transcript variant 3, mRNA.
种属: Mouse
CDS区长度: 3177 (查看编码区序列)
翻译后氨基酸长度: 1058 (查看氨基酸序列)
Transcript Variant: This variant (3) represents the longest transcript and encodes the shorter isoform (2). Variants 2, 3, and 4 encode the same isoform (2).
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G138610 小鼠 Uba1 (NM_001276316) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the ubiquitin-activating E1 family. The encoded protein initiates the ubiquitin activation and transfer cascade, catalyzing the first step in ubiquitin conjugation to mark cellular proteins for proteasome degradation. Ubiquitin activating enzymes use ATP to form a thioester between a conserved catalytic cysteine of the enzyme and the C-terminal carboxylate of ubiquitin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]