This locus encodes a member of the methyltransferase family, and is involved in chromatin remodeling. Transcripts from this locus can be induced or inhibited by cell stretch and affect cell differentiation in the myogenic or adipogenic pathways. Multiple transcript variants encoding different isoforms have been found for this gene. Additional splice variants have been described in the literature but they meet nonsense-mediated decay (NMD) criteria and are likely to be degraded as soon as they are transcribed. [provided by RefSeq, Jul 2008]
小鼠 Mettl8 (NM_001110512) cDNA克隆
| Accession: | NM_001110512 |
|---|---|
| 基因名称: | Mettl8 |
| 基因别名: | Tip; BC004636; RP23-359E23.1 |
| 基因描述: | Mus musculus methyltransferase like 8 (Mettl8), transcript variant b, mRNA. |
| 种属: | Mouse |
| CDS区长度: | 939 (查看编码区序列) |
| 翻译后氨基酸长度: | 312 (查看氨基酸序列) |
| Transcript Variant: | This variant (b), also known as TIP-5, uses an alternate in-frame splice site in the central coding region, compared to variant a. The resulting protein (isoform b), is shorter than isoform a. |
| 小鼠 Mettl8 (NM_145524) cDNA克隆 | transcript variant a |
| 小鼠 Mettl8 (NM_001110512) cDNA克隆 | transcript variant b |
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