小鼠 Brat1 (NM_181066) cDNA克隆

Accession: NM_181066
基因名称: Brat1
基因别名: Baat1; AA881470
基因描述: Mus musculus BRCA1-associated ATM activator 1 (Brat1), transcript variant 2, mRNA.
种属: Mouse
CDS区长度: 2469 (查看编码区序列)
翻译后氨基酸长度: 822 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and initiates translation at a downstream start codon, compared to variant 3. The encoded isoform (2) has a shorter N-terminus, compared to isoform 3.
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G140256 小鼠 Brat1 (NM_181066) cDNA克隆 pDONR223 2ug质粒 点击询价

A similar gene in human encodes a Breast Cancer 1 (BRCA1) interacting protein that is involved in cell cycle checkpoint signaling. The similar human protein is localized to DNA double strand breaks caused by ionizing radiation, and regulates cellular DNA damage response through interactions with Ataxia Telangiectasia Mutated (ATM) and DNA-dependent Protein Kinase. A pseudogene of this gene is located on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]