人 ATG4B (NM_013325) cDNA克隆

Accession: NM_013325
基因名称: ATG4B
基因别名: APG4B; AUTL1
基因描述: Homo sapiens autophagy related 4B, cysteine peptidase (ATG4B), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1182 (查看编码区序列)
翻译后氨基酸长度: 393 (查看氨基酸序列)
Transcript Variant: This variant (1) is the predominant transcript and it encodes the longer isoform (a).
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G140287 人 ATG4B (NM_013325) cDNA克隆 pDONR223 2ug质粒 点击询价

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]