人 RHOBTB2 (NM_015178) cDNA克隆

Accession: NM_015178
基因名称: RHOBTB2
基因别名: DBC2
基因描述: Homo sapiens Rho-related BTB domain containing 2 (RHOBTB2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2184 (查看编码区序列)
翻译后氨基酸长度: 727 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (3) is shorter than isoform 1.
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G140343 人 RHOBTB2 (NM_015178) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]