人 SRGAP2 (NM_015326) cDNA克隆

Accession: NM_015326
基因名称: SRGAP2
基因别名: FNBP2; SRGAP3; SRGAP2A; ARHGAP34
基因描述: Homo sapiens SLIT-ROBO Rho GTPase activating protein 2 (SRGAP2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 3216 (查看编码区序列)
翻译后氨基酸长度: 1071 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
产品编号 产品名称 载体 规格 价格
G140607 人 SRGAP2 (NM_015326) cDNA克隆 pDONR223 2ug质粒 点击询价

This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogous loci on human chromosome 1, resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Dec 2012]