人 BRD4 (NM_014299) cDNA克隆

Accession: NM_014299
基因名称: BRD4
基因别名: CAP; MCAP; HUNK1; HUNKI
基因描述: Homo sapiens bromodomain containing 4 (BRD4), transcript variant short, mRNA.
种属: Human
CDS区长度: 2169 (查看编码区序列)
翻译后氨基酸长度: 722 (查看氨基酸序列)
Transcript Variant: This variant (short) differs in the 3' UTR and coding region compared to variant long. The resulting isoform (short) is shorter and has a distinct C-terminus compared to isoform long.
产品编号 产品名称 载体 规格 价格
G140775 人 BRD4 (NM_014299) cDNA克隆 pDONR223 2ug质粒 点击询价
人 BRD4 (NM_058243) cDNA克隆 transcript variant long
人 BRD4 (NM_014299) cDNA克隆 transcript variant short

The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]