人 SCRIB (NM_015356) cDNA克隆

基本信息

Accession: NM_015356
基因名称: SCRIB
基因别名: CRIB1; SCRB1; SCRIB1; Vartul
基因描述: Homo sapiens scribbled planar cell polarity protein (SCRIB), transcript variant 2, mRNA.
种属: Human
CDS区长度: 4893 (查看编码区序列)
翻译后氨基酸长度: 1630 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G140845 人 SCRIB (NM_015356) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SCRIB (NM_182706) cDNA克隆 transcript variant 1
人 SCRIB (NM_015356) cDNA克隆 transcript variant 2

基因简介

This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

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