人 CABIN1 (NM_012295) cDNA克隆

Accession: NM_012295
基因名称: CABIN1
基因别名: CAIN; PPP3IN
基因描述: Homo sapiens calcineurin binding protein 1 (CABIN1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 6663 (查看编码区序列)
翻译后氨基酸长度: 2220 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same isoform (a).
产品编号 产品名称 载体 规格 价格
G140864 人 CABIN1 (NM_012295) cDNA克隆 pDONR223 2ug质粒 点击询价

Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms. [provided by RefSeq, Jan 2011]