人 FOSB (NM_006732) cDNA克隆

Accession: NM_006732
基因名称: FOSB
基因别名: AP-1; G0S3; GOS3; GOSB
基因描述: Homo sapiens FBJ murine osteosarcoma viral oncogene homolog B (FOSB), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1017 (查看编码区序列)
翻译后氨基酸长度: 338 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longer isoform (1).
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G140902 人 FOSB (NM_006732) cDNA克隆 pDONR223 2ug质粒 点击询价

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]