人 MAFF (NM_001161574) cDNA克隆

基本信息

Accession: NM_001161574
基因名称: MAFF
基因别名: U-MAF; hMafF
基因描述: Homo sapiens v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F (MAFF), transcript variant 5, mRNA.
种属: Human
CDS区长度: 408 (查看编码区序列)
翻译后氨基酸长度: 135 (查看氨基酸序列)
Transcript Variant: This variant (5) lacks the exon containing the translation start site compared to variant 3. The resulting isoform (b) is shorter at the N-terminus compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G141119 人 MAFF (NM_001161574) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 MAFF (NM_012323) cDNA克隆 transcript variant 1
人 MAFF (NM_001161572) cDNA克隆 transcript variant 3
人 MAFF (NM_001161573) cDNA克隆 transcript variant 4
人 MAFF (NM_001161574) cDNA克隆 transcript variant 5

基因简介

The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]

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