人 SLC24A2 (NM_001193288) cDNA克隆

Accession: NM_001193288
基因名称: SLC24A2
基因别名: NCKX2
基因描述: Homo sapiens solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 (SLC24A2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1935 (查看编码区序列)
翻译后氨基酸长度: 644 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (2) that is shorter than isoform 1.
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G143061 人 SLC24A2 (NM_001193288) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the calcium/cation antiporter superfamily of transport proteins. The encoded protein belongs to the SLC24 branch of exchangers, which can mediate the extrusion of one Ca2+ ion and one K+ ion in exchange for four Na+ ions. This family member is a retinal cone/brain exchanger that can mediate a light-induced decrease in free Ca2+ concentration. This protein may also play a neuroprotective role during ischemic brain injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]