人 GART (NM_001136006) cDNA克隆

Accession: NM_001136006
基因名称: GART
基因别名: AIRS; GARS; PAIS; PGFT; PRGS; GARTF
基因描述: Homo sapiens phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (GART), transcript variant 4, mRNA.
种属: Human
CDS区长度: 3033 (查看编码区序列)
翻译后氨基酸长度: 1010 (查看氨基酸序列)
Transcript Variant: This variant (4) contains a different segment for its 5' UTR, compared to variant 1. Variants 1, 3, and 4 encode the same protein.
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G144207 人 GART (NM_001136006) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a trifunctional polypeptide. It has phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase activity which is required for de novo purine biosynthesis. This enzyme is highly conserved in vertebrates. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]