人 TOX3 (NM_001146188) cDNA克隆

Accession: NM_001146188
基因名称: TOX3
基因别名: CAGF9; TNRC9
基因描述: Homo sapiens TOX high mobility group box family member 3 (TOX3), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1716 (查看编码区序列)
翻译后氨基酸长度: 571 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1.
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G145165 人 TOX3 (NM_001146188) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich due to CAG repeats in the coding sequence. A minor allele of this gene has been implicated in an elevated risk of breast cancer. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2009]