人 GLS (NM_014905) cDNA克隆

Accession: NM_014905
基因名称: GLS
基因别名: GAC; GAM; KGA; GLS1; AAD20
基因描述: Homo sapiens glutaminase (GLS), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2010 (查看编码区序列)
翻译后氨基酸长度: 669 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
产品编号 产品名称 载体 规格 价格
G145277 人 GLS (NM_014905) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]