人 DROSHA (NM_013235) cDNA克隆

Accession: NM_013235
基因名称: DROSHA
基因别名: RN3; ETOHI2; RNASEN; RANSE3L; RNASE3L; HSA242976
基因描述: Homo sapiens drosha, ribonuclease type III (DROSHA), transcript variant 1, mRNA.
种属: Human
CDS区长度: 4125 (查看编码区序列)
翻译后氨基酸长度: 1374 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
产品编号 产品名称 载体 规格 价格
G146175 人 DROSHA (NM_013235) cDNA克隆 pDONR223 2ug质粒 点击询价

Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al., 2002 [PubMed 12191433]). The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al., 2003 [PubMed 14508493]).[supplied by OMIM, Mar 2008]