人 GSN (NM_001127663) cDNA克隆

Accession: NM_001127663
基因名称: GSN
基因别名: ADF; AGEL
基因描述: Homo sapiens gelsolin (GSN), transcript variant 4, mRNA.
种属: Human
CDS区长度: 2304 (查看编码区序列)
翻译后氨基酸长度: 767 (查看氨基酸序列)
Transcript Variant: This variant (4) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (f) has a shorter and distinct N-terminus compared to isoform a.
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G146496 人 GSN (NM_001127663) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]