人 ANAPC4 (NM_001286756) cDNA克隆

Accession: NM_001286756
基因名称: ANAPC4
基因别名: APC4
基因描述: Homo sapiens anaphase promoting complex subunit 4 (ANAPC4), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2430 (查看编码区序列)
翻译后氨基酸长度: 809 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
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G147269 人 ANAPC4 (NM_001286756) cDNA克隆 pDONR223 2ug质粒 点击询价

A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of this gene product is not known. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]