人 FOXA2 (NM_021784) cDNA克隆

Accession: NM_021784
基因名称: FOXA2
基因别名: HNF3B; TCF3B
基因描述: Homo sapiens forkhead box A2 (FOXA2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1392 (查看编码区序列)
翻译后氨基酸长度: 463 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longer isoform (1).
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G148797 人 FOXA2 (NM_021784) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008]