人 APBA2 (NM_005503) cDNA克隆

基本信息

Accession: NM_005503
基因名称: APBA2
基因别名: X11L; MINT2; LIN-10; HsT16821; X11-BETA; D15S1518E; MGC:14091
基因描述: Homo sapiens amyloid beta (A4) precursor protein-binding, family A, member 2 (APBA2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2250 (查看编码区序列)
翻译后氨基酸长度: 749 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).

订购信息

产品编号 产品名称 载体 规格 价格
G149251 人 APBA2 (NM_005503) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 APBA2 (NM_005503) cDNA克隆 transcript variant 1
人 APBA2 (NM_001130414) cDNA克隆 transcript variant 2

基因简介

The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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