人 IARS (NM_002161) cDNA克隆

Accession: NM_002161
基因名称: IARS
基因别名: IRS; ILRS; IARS1; ILERS; PRO0785
基因描述: Homo sapiens isoleucyl-tRNA synthetase (IARS), transcript variant 1, mRNA.
种属: Human
CDS区长度: 3789 (查看编码区序列)
翻译后氨基酸长度: 1262 (查看氨基酸序列)
Transcript Variant: This variant (1) and variant 2 encode the functional protein.
产品编号 产品名称 载体 规格 价格
G149624 人 IARS (NM_002161) cDNA克隆 pDONR223 2ug质粒 点击询价

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found. [provided by RefSeq, Nov 2012]