人 IMPDH1 (NM_001142574) cDNA克隆

基本信息

Accession: NM_001142574
基因名称: IMPDH1
基因别名: IMPD; RP10; IMPD1; LCA11; sWSS2608
基因描述: Homo sapiens IMP (inosine 5'-monophosphate) dehydrogenase 1 (IMPDH1), transcript variant 6, mRNA.
种属: Human
CDS区长度: 1530 (查看编码区序列)
翻译后氨基酸长度: 509 (查看氨基酸序列)
Transcript Variant: This variant (6) differs in the 5' UTR and coding sequence and lacks an alternate in-frame segment compared to variant 1. The resulting isoform (f) is shorter at the N-terminus and lacks an internal segment compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G150244 人 IMPDH1 (NM_001142574) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 IMPDH1 (NM_000883) cDNA克隆 transcript variant 1
人 IMPDH1 (NM_183243) cDNA克隆 transcript variant 2
人 IMPDH1 (NM_001102605) cDNA克隆 transcript variant 3
人 IMPDH1 (NM_001142576) cDNA克隆 transcript variant 4
人 IMPDH1 (NM_001142573) cDNA克隆 transcript variant 5
人 IMPDH1 (NM_001142574) cDNA克隆 transcript variant 6
人 IMPDH1 (NM_001142575) cDNA克隆 transcript variant 7

基因简介

The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

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